Obstetrics, Pediatrics and Genetics

Overview

The Obstetrics, Pediatrics and Genetics area is focused on the research on the congenital malformations and pediatric diseases. The Fetal Maternal Medicine group creates synergies through the combined work of basic science researchers and clinical investigators in the preclinical basis of placental insufficiency complications and congenital heart disease. The Bio-Cell Fetal group, recently incorporated, studies basic pathophysiological mechanisms of fetal and pediatric congenital malformations, while the Growth and Development group does research on pediatric endocrine diseases. There is also a Genetics Medicine group that combines genetic diagnosis and research and is pioneer in Spain.

Publications

91

total

328

impact factor

3.60

average impact factor

Group Leader: Manuel Lopez Paredes

team

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The Bioengineering, Cell Therapy and Congenital Malformation Surgery research group is made up of clinical researchers (pediatric surgeons, neonatologists and obstetricians) and basic researchers (biochemists, biotechnologists and biologists), which make up a large multidisciplinary team with extensive experience in biomedical and clinical research.

The main objective of the different lines of research is to study the causes of human congenital malformations, especially spina bifida and congenital diaphragmatic hernia, and the development of new therapies based on advanced surgical techniques, as well as through use of cell therapy to promote tissue regeneration for therapeutic purposes and generate new treatments to alleviate or cure these serious pathologies. Our team develops a research with a great translational spirit to the human clinic, which has allowed our hospital to become a European reference center for prenatal repair of spina bifida.

11

total

28

impact factor

2^.57

average impact factor

SELECTED ARTICLES

Samuk I, Gine C, de Blaauw I, Morandi A, Stenstrom P, Giuliani S, Lisi G, Midrio P
Anorectal malformations and perineal hemangiomas: The Arm-Net Consortium experience.
J Pediatr Surg. 2019 Oct;54(10):1993-1997.
DOI: 10.1016/j.jpedsurg.2018.10.111
IF: 2,092
Oria M, Duru S, Figueira RL, Scorletti F, Turner LE, Fernandez-Alonso I, Fernandez-Martin A, Marotta M, Sbragia L, Shaaban AF, Peiro JL
Cell necrosis, intrinsic apoptosis and senescence contribute to the progression of exencephaly to anencephaly in a mice model of congenital chranioschisis.
Cell Death Dis. 2019 Sep 26;10(10):721.
J Pediatr Surg. 2017 Nov 23. pii: S0022-3468(17)30771-6.
DOI: 10.1038/s41419-019-1913-6.
IF: 5,638
Nunez-Ramiro A, Benavente-Fernandez , Valverde E, Cordeiro M, Blanco D, Boix H, Cabanas F, Chaffanel M, Fernandez-Colomer B, Fernandez-Lorenzo JR, Kuligowski J, Loureiro B, Moral-Pumarega MT, Pavon A, Sanchez-Illana A, Tofe I, Hervas D, Garcia-Robles A, Parra-Llorca A, Cernada M, Martinez-Rodilla J, Lorente-Pozo S, Llorens R, Marques R, Vento M
Topiramate plus Cooling for Hypoxic-Ischemic Encephalopathy: A Randomized, Controlled, Multicenter, Double-Blinded Trial.
Neonatology. 2019 May 15;116(1):76-84.
DOI: 10.1159/000499084
IF: 2,688
Gander R, Asensio M, Molino JA, Royo GF, Lara LE, Lopez M, Ariceta G
Outcome of kidney transplantation from young pediatric donors (aged less than 6 years) to young size-matched recipients.
J Pediatr Urol. 2019 May;15(3):213-220.
DOI: 10.1016/j.jpurol.2019.03.015.
IF: 1,736
Gallardo-Calero I, Barrera-Ochoa S, Manzanares MC, Sallent A, Vicente M, Lopez-Fernandez A, De Albert M, Aguirre M, Soldado F, Velez R
Vascularized Periosteal Flaps Accelerate Osteointegration and Revascularization of Allografts in Rats.
Clin Orthop Relat Res. 2019 Apr;477(4):741-755.
DOI: 10.1097/CORR.000000000000040
IF: 4,154

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