Neurosciences

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Overview

The Neuroscience area is consolidating its position as one of the largest clusters of research labs working on neurological diseases across Europe. At present, the area comprises 14 groups with more than one hundred fully dedicated researchers in close contact with top clinicians in the hospital. These research groups pursue a better and multifaceted understanding of the etiopathogenic mechanisms underlying a large variety of mostly adult but also pediatric neurological disorders including stroke, multiple sclerosis, Alzheimer’s disease, Parkinson’s disease, primary headaches, epilepsy, neuromuscular disorders, and also neurosurgical and psychiatric pathologies. The area also integrates groups involved in neuroimaging, analysis and interpretation of high-throughput data, and gene therapy strategies to target inflammatory and neurodegenerative neurological conditions.

Publications

276
total
1952
impact factor
7.07
average impact factor

Group Leader: Estevo Santamarina Pérez

Among the research advances of the Epilepsy Group during 2019, we highlight the obtaining of a pre-hospital clinical scale (ADAN) to identify patients with status, the study of perfusion CT in focal status, the development of epilepsy in post-stroke status, the progress in the study of biomarkers for predicting new epileptic seizures, and how epilepsy and antiepileptic drugs affect patients ’cognitive performance and quality of life.

Two research lines (Epilepsy and sleep disorders, and Cognitive assessment and neuroimaging in epilepsy) were started with the incorporation of two young clinical investigators into the group (Ivan Seijo, Elena Fonseca).

Clinical trials initiated in 2019 were XPF-008-201(XEN1101) for focal epilepsy, and EP0092/EP0093(Padsevonil) for drug-resistant epilepsy.

The new continuous monitoring unit with 24-hour videoEEG has improved the diagnosis of patients with epilepsy and must favor the development of new research studies and the capture of new clinical trials.

VHIR Annual Report 2019