Infectious Diseases

Overview

The groups of this area aim to improve the outcomes of patients with infectious diseases. The Epidemiology and Public Health group focuses on the epidemiology and prevention of healthcare acquired infections, transmissible infections and on the new vaccines. The Infectious Diseases group focuses on improving the strategies of clinical problems observed in clinical practice. The Microbiology group studies the mechanisms of antimicrobial resistance, pathogenicity, genomic epidemiology and infectious diseases diagnostics. The CRIPS group focuses on developing translational and clinical research in critical care, while the SODIR group works in the areas of sepsis, organ dysfunction and resuscitation. There is also a group focused on clinical research on children’s infectious diseases and primary immunodeficiencies. Finally, the CIBBIM-Nanomedicine group Works in the synthesis, characterization and applications of engineered inorganic nanoparticles in the field of infectious diseases.

Publications

260

total

1322

impact factor

5.08

average impact factor

Group Leader: Ricard Ferrer Roca

team

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The sepsis research line has participated in establishing new research priorities for sepsis and septic shock and how multifaceted educational intervention improves antibiotic treatment. This line is specially interested on the identification of biomarkers for the early diagnosis and stratification of septic patient. The acute respiratory failure research line published two important studies regarding the use of high flow nasal cannula supportive therapy and weaning strategies from mechanical ventilation.

SODIR has two ongoing funded projects (Health Institute Carlos III). The first study aims to analyze the DNA of the donor and its relationship with the pulmonary inflammatory response and the objective of the second study is to characterize patients with hemophagocytic syndrome.

SODIR is considered as an emerging research group by AGAUR. SODIR also has an important Clinical Research Unit that centralizes all the clinical trials that are carried out in the group.

30

total

283

impact factor

9^.44

average impact factor

SELECTED ARTICLES

Subirà C, Hernández G, Vázquez A, Rodríguez-García R, González-Castro A, García C, Rubio O, Ventura L, López A, de la Torre MC, Keough E, Arauzo V, Hermosa C, Sánchez C, Tizón A, Tenza E, Laborda C, Cabañes S, Lacueva V, Fernández MM, Arnau A, Fernández R
Effect of Pressure Support vs T-Piece Ventilation Strategies During Spontaneous Breathing Trials on Successful Extubation Among Patients Receiving Mechanical Ventilation: A Randomized Clinical Trial
JAMA. 2019 Jun 11;321(22):2175-2182. doi: 10.1001/jama.2019.7234.
IF: 51,27
Timsit JF, Sonneville R, Kalil AC, Bassetti M, Ferrer R, Jaber S, Lanternier F, Luyt CE, Machado F, Mikulska M, Papazian L, Pène F, Poulakou G, Viscoli C, Wolff M, Zafrani L, Van Delden C.
Diagnostic and therapeutic approach to infectious diseases in solid organ transplant recipients.
Intensive Care Med. 2019 May;45(5):573-591. doi: 10.1007/s00134-019-05597-y
IF: 18,97
Roca O, Caralt B, Messika J, Samper M, Sztrymf B, Hernández G, García-de-Acilu M, Frat JP, Masclans JR, Ricard JD.
An Index Combining Respiratory Rate and Oxygenation to Predict Outcome of Nasal High-Flow Therapy.
Am J Respir Crit Care Med. 2019 Jun 1;199(11):1368-1376. doi: 10.1164/rccm.201803-0589OC.
IF: 16,49
Lorente-Sorolla C, Garcia-Gomez A, Català-Moll F, Toledano V, Ciudad L, Avendaño-Ortiz J, Maroun-Eid C, Martín-Quirós A, Martínez-Gallo M, Ruiz-Sanmartín A, Del Campo ÁG, Ferrer-Roca R, Ruiz-Rodriguez JC, Álvarez-Errico D, López-Collazo E, Ballestar E.
Inflammatory cytokines and organ dysfunction associate with the aberrant DNA methylome of monocytes in sepsis.
Genome Med. 2019 Oct 29;11(1):66. doi: 10.1186/s13073-019-0674-2
IF: 10,89
Dey P, Fabri-Faja N, Calvo-Lozano O, Terborg RA, Belushkin A, Yesilkoy F, Fàbrega A, Ruiz-Rodriguez JC, Ferrer R, González-López JJ, Estévez MC, Altug H, Pruneri V, Lechuga LM.
Label-free Bacteria Quantification in Blood Plasma by a Bioprinted Microarray Based Interferometric Point-of-Care Device.
ACS Sens. 2019 Jan 25;4(1):52-60. doi: 10.1021/acssensors.8b00789.
IF: 6,94

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